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When Should a Microfluidic Device Move from PDMS to Injection Molding?
Microfluidics manufacturing at scale demands more than a good prototype. The path from a validated PDMS chip to a reproducible, production-ready custom microfluidic device is where most R&D programs stall and microfluidic injection molding is how the best teams cross that gap. The Reproducibility Wall Every Researcher Hits Microfluidics manufacturing is a discipline with a reproducibility problem and it starts long before production. You've validated the assay. The droplet ge
Lina
May 2111 min read


Microfluidic Chip Manufacturing for Point-of-Care Diagnostics: PMMA-to-PMMA Bonding at Production Scale
Project Requirements The chip architecture imposed strict technical requirements: Microchannel geometry with tight dimensional tolerances and no draft radius compensation Optical clarity for accurate signal detection, including in bonding-affected regions Dimensional stability after bonding PMMA-to-PMMA bonding without microchannel deformation At this scale, tool design, microchannel size and density, combined with material processing conditions, can result in incomplete fill
Lina
May 53 min read
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